Research Article

Postprandial gall-bladder emptying in patients with gall stones.

Br Med J 1980; 280 doi: (Published 19 January 1980) Cite this as: Br Med J 1980;280:141
  1. D P Maudgal,
  2. R M Kupfer,
  3. P L Zentler-Munro,
  4. T C Northfield


    Gall-bladder emptying in response to a standard meal was assessed in 34 patients with radiolucent gall stones and 34 matched controls. Percentage gall-bladder emptying, derived from volume measurements made on standardised oral cholecystography, was significantly higher at 15 minutes in the patients than the controls (mean +/- SE of mean 38.0 +/- 3.7% v 28.0 +/- 3.8%). This difference was maintained at 30 and 60 minutes. It is concluded that postprandial gall-bladder emptying is increased in patients with cholesterol gall stones, and that this may be the cause of the small bile-acid pool found in these patients.