Research Article

Influence of postoperative empyema on survival after pulmonary resection for bronchogenic carcinoma.

Br Med J 1978; 2 doi: (Published 11 November 1978) Cite this as: Br Med J 1978;2:1329
  1. H Minasian,
  2. C T Lewis,
  3. S J Evans


    Fifty patients who had developed empyema after pulmonary resection for primary carcinoma of the lung were individually paired with patients who had not suffered this complication. Pairs were matched as far as possible for age, sex, extent of operation, histology of tumour, extent of primary spread, extent of lymphatic spread, and use of postoperative radiotherapy. Analysis of survival times both for the matched pairs and for the two groups of patients showed no significant difference in long-term survival. The results suggest that any immunological suppression of carcinoma cells due to sepsis in the pleural space is ineffective in prolonging survival.