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Research Article

Combined dexamethasone and low-molecular-weight dextran in acute brain infarction: double-blind study.

Br Med J 1976; 2 doi: (Published 11 December 1976) Cite this as: Br Med J 1976;2:1409
  1. M Kaste,
  2. R Fogelholm,
  3. O Waltimo


    Intramuscular dexamethasone combined with intravenous low-molecular-weight dextran (dextran 40) was compared with placebo in 40 patients with acute ischaemic cerebral infarction. A double-blind procedure was used. Dexamethasone was given for up to 14 days and dextran 40 for up to three days after the infarction. A weighted scoring system was used to evaluate neurological state and mobility. There were no differences in mortality or in improvement of the neurological or mobility scores between the two groups.