Research Article

Falciparum malaria cured by quinine followed by sulfadoxine-pyrimethamine.

Br Med J 1975; 2 doi: (Published 05 April 1975) Cite this as: Br Med J 1975;2:15
  1. A P Hall,
  2. E B Doberstyn,
  3. V Mettaprakong,
  4. P Sonkom


    Quinine (at least four doses given at intervals of eight to 12 hours) followed by a single dose of sulfadoxine-pyrimethamine (Fansidar) is the most effective treatment of chloroquine-resistant falciparum malaria. This regimen cured 96% of patients (302 out of 314) with an average initial parasite count of 90 X 10-9/1.