Urinary Excretion of Fibrinogen-related Materials, Complement, and Immunoglobulins in Proliferative Glomerulonephritis and after Renal TransplantationBr Med J 1974; 2 doi: https://doi.org/10.1136/bmj.2.5918.535 (Published 08 June 1974) Cite this as: Br Med J 1974;2:535
- M. S. Hoq,
- J. L. Anderton,
- M. Cunningham,
- John D. Cash
Using a radial immunodiffusion technique we measured the urinary concentration of material related to complement (C3), IgM, and IgG along with fibrin-fibrinogen degradation products and heterophile (sheep) haemagglutinins in 15 patients with proliferative glomerulonephritis and in 10 patients after renal transplantation. There was a significant correlation between all variables measured, and serial studies showed that with the exception of IgG-related materials potentially useful information could be obtained on the detection of rejection and the response to treatment in both conditions. The significance of these observations is discussed.