Effect of Late Night Calcium Supplements on Overnight Urinary Calcium Excretion in Premenopausal and Postmenopausal WomenBr Med J 1973; 2 doi: https://doi.org/10.1136/bmj.2.5865.510 (Published 02 June 1973) Cite this as: Br Med J 1973;2:510
- P. E. Belchetz,
- Margaret H. Lloyd,
- R. G. S. Johns,
- R. D. Cohen
The overnight urinary calcium/creatinine ratio is higher in the early years after the menopause than before it. However, the increment of urinary calcium/creatinine after a late evening calcium supplement is less in early postmenopausal than in premenopausal women. It is suggested that calcium therapy in postmenopausal osteoporosis may be best administered as a single late evening dose rather than in divided doses throughout the day.