Papers And Originals

Effect of Late Night Calcium Supplements on Overnight Urinary Calcium Excretion in Premenopausal and Postmenopausal Women

Br Med J 1973; 2 doi: (Published 02 June 1973) Cite this as: Br Med J 1973;2:510
  1. P. E. Belchetz,
  2. Margaret H. Lloyd,
  3. R. G. S. Johns,
  4. R. D. Cohen


    The overnight urinary calcium/creatinine ratio is higher in the early years after the menopause than before it. However, the increment of urinary calcium/creatinine after a late evening calcium supplement is less in early postmenopausal than in premenopausal women. It is suggested that calcium therapy in postmenopausal osteoporosis may be best administered as a single late evening dose rather than in divided doses throughout the day.