Papers And Originals

Diphtheria-Tetanus-Pertussis Immunization by Intradermal Jet Injection

Br Med J 1972; 2 doi: (Published 22 April 1972) Cite this as: Br Med J 1972;2:197
  1. J. P. Stanfield,
  2. P. M. Bracken,
  3. K. M. Waddell,
  4. D. Gall


    An intradermal jet injector was used to administer combined diphtheria, tetanus, and pertussis (D.T.P.) vaccines to infants aged 2 to 12 months. A second dose was given one month after the first and a third six months after the second. Each dose was considerably smaller than the standard intramuscular dose. Blood samples taken one month after the third dose showed a satisfactory diphtheria and tetanus antitoxin response in all but a few cases. The antibody response to the pertussis component was not examined. Reactions were insignificant. Intradermal jet injection is proposed as a cheap, extremely rapid, and effective technique for D.T.P. immunization, especially suitable for use in remote areas where trained staff and facilities are few and many children require immunization.