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Practolol in Treatment of Angina Pectoris. A Double-blind Trial

Br Med J 1970; 2 doi: (Published 16 May 1970) Cite this as: Br Med J 1970;2:402
  1. C. F. George,
  2. R. E. Nagle,
  3. B. L. Pentecost


    Twenty-four patients with angina pectoris entered a double-blind trial of the cardioselective beta-adrenergic blocking agent practolol. Seventeen experienced less angina and consumed fewer glyceryl trinitrate tablets when on the active preparation. There was also a decrease in the mean number of attacks suffered by patients while on practolol and a reduction in the number of glyceryl trinitrate tablets taken. These results are of statistical significance at, at least, the 5% level.