Papers And Originals

Combined Thyroxine and Triiodothyronine for Thyroid Replacement Therapy

Br Med J 1970; 2 doi: (Published 02 May 1970) Cite this as: Br Med J 1970;2:270

This article has a correction. Please see:

  1. Selwyn Taylor,
  2. M. Kapur,
  3. Ross Adie


    Tablets containing 50μg. of thyroxine and 15μg. of triiodothyronine have been used to treat patients with hypothyroidism of varied aetiology. Following total thyroidectomy a daily dose of three tablets—that is, 150μg. of thyroxine and 45μg. of triiodothyronine—maintained patients in a euthyroid state and produced a protein-bound iodine level within the normal range. The preparation is preferable to dried thyroid because of uniformity of activity and speed of action, and when the patient is clinically euthyroid the P.B.I. falls within the normal range.