Treatment of Acne Vulgaris with Tetracyline Hydrochloride: a Double-blind Trial with 51 PatientsBr Med J 1969; 2 doi: https://doi.org/10.1136/bmj.2.5649.76 (Published 12 April 1969) Cite this as: Br Med J 1969;2:76
- Peter Lane,
- Donald M. Williamson
Fifty-one patients with acne vulgaris were included in a double-blind trial to assess the therapeutic effect of 250 mg. tetracycline hydrochloride twice daily for three months. The results, assessed clinically and photographically, showed that tetracycline hydrochloride had a statistically significant beneficial effect. Hence, since it is cheap and rarely has side-effects in healthy young adults, its use is suggested, as well as local therapy, in the more severe forms of acne.