Intended for healthcare professionals

Research Article

Stilboestrol and vaginal clear-cell adenocarcinoma syndrome.

Br Med J 1978; 1 doi: (Published 17 June 1978) Cite this as: Br Med J 1978;1:1588
  1. J M Monaghan,
  2. L A Sirisena


    A vaginal clear-cell adenocarcinoma developed in a young woman who had been exposed in utero to maternal stilboestrol treatment. During 1940-71 in the UK some 7500 women were given stilboestrol during pregnancy. Thus more cases are likely to appear and clinicians caring for young women should be alert to this possibility.