Research Article

Angiotensin II in essential hypertension.

Br Med J 1977; 1 doi: (Published 12 February 1977) Cite this as: Br Med J 1977;1:415
  1. D G Beevers,
  2. J J Morton,
  3. C S Nelson,
  4. P L Padfield,
  5. M Titterington,
  6. M Tree


    Plasma concentrations of angiotensin II (PAC) were measured in a group of 146 hypertensive patients (diastolic pressure greater than 105 mm Hg) who had no apparent underlying cause for their condition and 113 randomly selected normotensive controls (diastolic pressure less than 90 mm Hg). There was no evidence of bimodality in the frequency distribution curves for plasma angiotensin II concentrations among the hypertensive patients. It was concluded that hypertension associated with low angiotensin II concentration and by implication "low-renin" hypertension is not a condition separate from essential hypertension.