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Research Article

Polyarthritis in adults with hypogammaglobulinaemia and its rapid response to immunoglobulin treatment.

Br Med J 1976; 1 doi: (Published 29 May 1976) Cite this as: Br Med J 1976;1:1314
  1. A D Webster,
  2. G Loewi,
  3. R D Dourmashkin,
  4. D N Golding,
  5. D J Ward,
  6. G L Asherson


    Five patients with primary hypogammaglobulinaemia developed a severe polyarthritis that had some features in common with rheumatoid arthritis. Their joint disease could be distinguished from rheumatoid arthritis, however, by the dramatic improvement after gammaglobulin treatment. The arthritis of hypogammaglobulinaemia can, therefore, be included among the few potentially curable polyarthritides.