Research Article

Once-daily dosing with Atenolol in patients with mild or moderate hypertension.

Br Med J 1976; 1 doi: (Published 24 April 1976) Cite this as: Br Med J 1976;1:990
  1. A P Douglas-Jones,
  2. J M Cruickshank


    Because of the difficulties patients have in adhering to their drug regimens a trial was performed in which patients with essential hypertension were given, in random order and for four weeks each, three different doses of atenolol to be taken once daily. Atenolol effectively decreased lying and standing blood pressures, and there was no difference between the effects of the three doses. The simplicity of the regimen, as well as atenolol's freedom from troublesome side effects, should be valuable in helping patients adhere to long-term treatment.