Intended for healthcare professionals

Research Article

Fetal complications of obstetric cholestasis.

Br Med J 1976; 1 doi: https://doi.org/10.1136/bmj.1.6014.870 (Published 10 April 1976) Cite this as: Br Med J 1976;1:870
  1. R Reid,
  2. K J Ivey,
  3. R H Rencoret,
  4. B Storey

    Abstract

    Among 56 pregnancies complicated by obstetric cholestasis five intrauterine deaths and one neonatal death occurred between 33 and 39 weeks, and a further six infants required urgent delivery for intrapartum asphyxia. Eighteen spontaneous premature deliveries occurred. Five mothers required specific treatment for unexplained postpartum haemorrhage. Cholestasis of pregnancy is therefore not a condition benign to the fetus, and it may contribute to increased maternal morbidity.