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Research Article

Pericarditis, pleural effusion, and pneumonitis with transient mitochondrial antibodies.

Br Med J 1975; 1 doi: (Published 15 February 1975) Cite this as: Br Med J 1975;1:370
  1. J Guardia,
  2. J Gomez,
  3. C Martin,
  4. J M Martinez-Vazquez,
  5. R Bacardi,
  6. J Tornos


    Four women with fever, arthromyalgias, pericarditis, pleural effusion, high erythrocyte sedimentation rates, and lymphopenia had mitochondrial antibodies in the serum in the absence of antinuclear antibody. Their illness lasted 5-12 weeks and the antibody test results became negative on remission. Absence of specific bacteriological findings, normal antistreptolysin O titres, resistance to antibiotics, and good response to steroids suggested that these cases represented a milder and less persistent form of the syndrome resembling systemic lupus erythematosus described by German authors.