Research Article

Gamma-glutamyl transpeptidase, triglycerides, and enzyme induction.

Br Med J 1975; 1 doi: (Published 04 January 1975) Cite this as: Br Med J 1975;1:17
  1. P J Martin,
  2. J V Martin,
  3. D M Goldberg


    A study conducted on 109 consecutive patients submitted for routine lipid and lipoprotein screening has shown a significant positive association between serum gamma-glutamyl transpeptidase (gamma-GT) activity and the serum triglyceride concentration and between serum gamma-GT activity and the serum pre-beta-lipoprotein concentration. We suggest that these associations may reflect hepatic microsomal enzyme induction in hyperlipidaemic subjects which increases the hepatic content of the rate-limiting enzyme(s) for triglyceride synthesis.