Papers And Originals

Total Screening of Blood Donations for Australia (Hepatitis Associated) Antigen and its Antibody

Br Med J 1972; 1 doi: (Published 11 March 1972) Cite this as: Br Med J 1972;1:663
  1. J. Wallace,
  2. G. R. Milne,
  3. A. Barr


    During a period of one year all of 105,724 blood donations were tested for Australia (Au) antigen and its antibody by rapid immunoelectro-osmophoresis—86 (1 in 1,229) were positive for antigen and 67 (1 in 1,578) positive for antibody. Second donations by previously negative donors reduce the overall incidence of positives. Men prisoners have a significantly higher incidence of Au antigen (1 in 153) than non-institutionalized men (1 in 803). The latter have a significantly higher incidence of antigen than women (1 in 2,019). Only one antigen-positive donor was incubating acute viral hepatitis. Failure to detect one strong and one weak antigen was responsible for two cases of posttransfusion Au-antigen-positive hepatitis.