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Medical Practice

Halothane Hepatitis—A Preventable Disease?

Br Med J 1971; 1 doi: (Published 20 February 1971) Cite this as: Br Med J 1971;1:448
  1. Paul Sharpstone,
  2. D. R. K. Medley,
  3. Roger Williams


    Eleven patients with acute hepatitis following multiple anaesthetics with halothane have been seen at two hospitals during the last four years. Six had massive hepatic necrosis and died. Unexplained fever occurred in nine of the patients; two of these and one other had had previous episodes of jaundice after halothane anaesthesia. Thus, in ten patients the disease could have been avoided.

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