Papers And Originals

Insulin Antagonist of Pituitary Origin in Plasma of Normal and Diabetic Subjects

Br Med J 1971; 1 doi: (Published 23 January 1971) Cite this as: Br Med J 1971;1:203
  1. P. Zimmet,
  2. F. M. Ng,
  3. J. Bornstein,
  4. J. McD. Armstrong,
  5. H. P. Taft


    Studies on ultrafiltrates of the plasma of normal and diabetic subjects have shown that a polypeptide of similar characteristics to the growth-hormone-derived polypeptide In-G is present in higher concentrations in diabetic subjects, thus indicating a possible role in the pathogenesis of diabetes mellitus. The polypeptide is absent from the plasma of hypophysectomized diabetic patients.