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Agglutinin Response to Pertussis Vaccination in the Child

Br Med J 1971; 1 doi: (Published 09 January 1971) Cite this as: Br Med J 1971;1:86
  1. J. D. Abbott,
  2. N. W. Preston,
  3. R. I. Mackay


    Children were immunized with plain pertussis vaccine made by three manufacturers in 1967. After a primary course of three injections at monthly intervals, starting at 3-4 months of age, the agglutinin response was poor. Even after a “booster” dose, given five months later, not all of the vaccines had stimulated a response to all three pertussis agglutinogens. A further investigation with current vaccines of different kinds administered according to more than one schedule is recommended.