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Erythropoietic Protoporphyria IV. Protection from Sunlight

Br Med J 1970; 1 doi: (Published 21 March 1970) Cite this as: Br Med J 1970;1:730
  1. Ramon M. Fusaro,
  2. Walter J. Runge


    Dihydroxyacetone and lawsone, in a vanishing cream base, applied to the skin was found to protect patients with erythropoietic protoporphyria against sunlight. The use of the same ingredients in a 50% isopropyl alcohol/water solution did not induce adequate light protection. The chemically induced ultraviolet light filter in the stratum corneum allowed these patients to change their lives from an “indoor” to an “outdoor” environment.


    • * The value of normal erythrocyte protoporphyrin is 15-65 μg./100 ml. of blood and not the printer's error of 565 μg. as seen in our first article (Peterka et al., 1965).