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Papers And Originals

Contraception with Chlormadinone Acetate in Woman with Previous Contraceptive Jaundice

Br Med J 1970; 1 doi: (Published 17 January 1970) Cite this as: Br Med J 1970;1:152
  1. R. P. H. Thompson,
  2. Roger Williams


    The oral contraceptive chlormadinone acetate has been given for eight months to a woman who had developed jaundice during four pregnancies, and twice while taking a combined contraceptive pill. No side-effects or changes in liver function were observed. This is further evidence that progestogens used for contraception, and in particular those derived from hydroxyprogesterone, are less hepatotoxic than the oestrogenic components.