Papers And Originals

Acetazolamide and Sodium Bicarbonate in Treatment of Salicylate Poisoning in Adults

Br Med J 1969; 1 doi: (Published 04 January 1969) Cite this as: Br Med J 1969;1:16
  1. A. G. Morgan,
  2. A. Polak


    Ten adults suffering from salicylate overdosage were treated successfully with a combination of sodium bicarbonate and acetazolamide to exploit the increase in salicylate clearance which is known to occur in very alkaline urine. The advantages of the method include the absence of important complications and the small volume of fluid required.