Intended for healthcare professionals

Raising the bar for using surrogate endpoints in drug regulation and health technology assessment

Raising the bar for using surrogate endpoints in drug regulation and health technology assessment

Surrogate endpoints provide no guarantee of clinical benefit and should be used only as a last resort in drug trials, argue these authors

Feature∙Should regulatory authorities approve drugs based on surrogate endpoints?Opinion∙Surrogate endpoints need complementary patient reported outcomes

A woman during a healthcare consultation

Menstrual changes after covid-19 vaccination

Changes to periods have been experienced shortly after covid-19 vaccination. We are still awaiting definitive evidence, says Victoria Male, but in the interim how should clinicians counsel patients?

editorial | Sep 16

Menstrual changes after covid-19 vaccination

Changes to periods have been experienced shortly after covid-19 vaccination. We are still awaiting definitive evidence, says Victoria Male, but in the interim how should clinicians counsel patients?

editorial

Sep 16

Helen Salisbury: Trouble with the new normal

We’re being encouraged to accept that 130 deaths a day from a preventable infectious disease is unremarkable. I beg to differ, says Helen Salisbury

opinion | Sep 14

Helen Salisbury: Trouble with the new normal

We’re being encouraged to accept that 130 deaths a day from a preventable infectious disease is unremarkable. I beg to differ, says Helen Salisbury

opinion

Sep 14

Vaccinating people who have had covid-19: why doesn’t natural immunity count in the US?

Evidence is mounting that natural immunity is at least as protective as vaccination, yet public health leadership says everyone needs the vaccine. Jennifer Block investigates

feature | Sep 13

Vaccinating people who have had covid-19: why doesn’t natural immunity count in the US?

Evidence is mounting that natural immunity is at least as protective as vaccination, yet public health leadership says everyone needs the vaccine. Jennifer Block investigates

feature

Sep 13

Government is urged to tackle “punitive pension taxation” to stop doctors retiring early

news | Sep 15

Cross government strategy needed to reduce health inequalities, says alliance

news | Sep 15

BMA moves to neutral position on assisted dying

news | Sep 14

Covid-19: Booster doses to be offered to 30 million people in UK

news | Sep 14

Clare Gerada: From clap to slap—general practice in crisis

opinion | Sep 14

Covid-19: Long covid must be recognised as occupational disease, says BMA

news | Sep 14

How can I manage conflict in my team?

careers | Sep 13

Latest articles

Given public support and broad shifts to permit assisted dying, it seems more likely a question of when, not if, for legalisation in the UK. This is an issue on which all UK doctors should now engage

editorial

Sep 9

Doctors’ organisations, neutrality, and the assisted dying debate

Some doctors say that neutrality is the best way for organisations such as the BMA to represent members’ diverse views on legalising medical help to die, while others say that it indicates tacit support and can mask strong objections

feature

Sep 9

Euthanasia and assisted dying: the illusion of autonomy—an essay by Ole Hartling

feature | Sep 9

It is vital we have data to support the debate on assisted dying

opinion | Sep 9

There is nothing holy about agony: religious people and leaders support assisted dying too

feature | Sep 9

Assisted dying around the world

feature | Sep 10

Climate emergency

Call for emergency action to limit global temperature increases, restore biodiversity, and protect health

The greatest threat to global public health is the continued failure of world leaders to keep the global temperature rise below 1.5°C. More than 200 health journals across the world have come together to publish this Editorial urging governments to act

editorial

Sep 6

Climate action for health and hope