Re: Raised inflammatory markers

14 February 2012

Watson et al state that normal inflammatory markers make myeloma very unlikely as a diagnosis and rules out the need for further testing. This is dangerous advice, as patients with light chain myeloma, non-secretory myeloma, or simply a low paraprotein level, can have a normal plasma viscosity. There is no 'rule out test' for myeloma: bloods, urine, radiology, and bone marrow all need to be taken into consideration.

Competing interests: None declared

Gwendolen Al Wakeel, Haematology Associate Specialist

North Bristol NHS Trust, Southmead Hospital, Bristol BS10 5NB

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