Thank you for an interesting article with good pictures. I'd just like to ask you to check some statistics.

If, as you state, the prevalence of Raynaud's is 6-20% in women and 12.5% of those with Raynaud's develop scleroderma, this would suggest that about 1.6% of the female popluation will develop scleroderma. This however is clearly not the case (perhaps about a 50x overestimate?). I suspect what you have done is mixed up population prevalence of Raynaud's (6-20%) with progression to scleroderma in a secondary care population (12.5%).

It perhaps would be helpful if this were clearer in the article, in order not to alarm those with a common mainly harmless if annoying condition and GPs dealing with a primary care population. I'd welcome the authors' response to this.

Competing interests: I have primary Raynaud's phenomenon