This article is interesting in the way the Indian community is
divided based on sociodemographic factors, but there is a lot of room here
for confouding bias. This is particularly true because in India,
sociodemographic factors have a key role in determining a person's
lifestyle and day to day activities. One of the confounding factors here
could be the level of physical activity/inactivity as the lower
socioeconomic groups in India tend to more physically active than the
higher groups and the genetic composition and risk factors would be
different. The last several decades have witnessed the higher groups in
rural India doing clerical and proffesional work while the lower groups
doing mostly manual labour which might have an influence at the genetic
level in terms of risk factors, eventhough this is changing gradually.
Also, the lower groups tend to snack less on junk food, use less of
transfatty acids,refined food products and saturated fats than the higher
group.
Rapid Response:
Room for bias
This article is interesting in the way the Indian community is
divided based on sociodemographic factors, but there is a lot of room here
for confouding bias. This is particularly true because in India,
sociodemographic factors have a key role in determining a person's
lifestyle and day to day activities. One of the confounding factors here
could be the level of physical activity/inactivity as the lower
socioeconomic groups in India tend to more physically active than the
higher groups and the genetic composition and risk factors would be
different. The last several decades have witnessed the higher groups in
rural India doing clerical and proffesional work while the lower groups
doing mostly manual labour which might have an influence at the genetic
level in terms of risk factors, eventhough this is changing gradually.
Also, the lower groups tend to snack less on junk food, use less of
transfatty acids,refined food products and saturated fats than the higher
group.
Competing interests: No competing interests