Intended for healthcare professionals

Rapid response to:

Endgames Statistical Question

Study design

BMJ 2009; 339 doi: https://doi.org/10.1136/bmj.b5263 (Published 10 December 2009) Cite this as: BMJ 2009;339:b5263

Rapid Response:

Truly blinded?

I would argue that this study is not even single blinded and that
answer c is incorrect. I think it would be quite obvious when inserting a
cannula to detect if a person's hand was warmer than usual, although it
must be noted that the nurse anaesthetist was 'unaware' of the study
hypothesis according to the original publication. Whether this was actually
achieved is debatable but given the nature of the intervention, the study
would then be susceptible to performance bias.

Competing interests:
None declared

Competing interests: No competing interests

11 December 2009
Richard Mc Gee
PhD Student
Centre for Kidney Research, Westmead Childrens Hospital, Westmead, NSW, Australia