Intended for healthcare professionals

Rapid response to:

Practice Lesson of the Week

Metformin associated lactic acidosis

BMJ 2009; 339 doi: https://doi.org/10.1136/bmj.b3660 (Published 16 September 2009) Cite this as: BMJ 2009;339:b3660

Rapid Response:

Metformin and General Anaesthesia

The recommendations for withdrawal of Metformin table in the original article is deceptive. It is clearly incorrect to quote information from 2008 NICE guidelines along with that from an Editorial in 2003. The advice to withdraw metformin 2 days before general anaesthesia is from the editorial by Jones and had no evidence to back it up.

Furthermore (and as rapid responders pointed out in 2003), it is not anaesthesia that is a factor in the development of lactic acidosis but surgery itself. It is my practice to withdraw Metformin only on the night prior to surgery and this is standard practice in departments I have worked in recently.

It is disappointing that inacuracies get reprinted in this way.

Competing interests: None declared

Competing interests:

06 December 2009
Alistair May
Anaesthesia
Stirling Royal Infirmary, Scotland FK8 2AU