Physical activity, coronary artery disease and depression: some connections!
Dear sir:
Notably, a large body of research data as also emphasized in this
impressive editorial by Batty and Lee (2004) suggests robustly the
protective effect of physical excercise in leisure time on the development
of coronary artery disease (CAD). Possibly, other diseases such as
diabetes mellitus, stroke, cancers, and osteoporosis are also positively
affected by physical exercise, which is reported to have an inverse
relationship with these diseases including CAD coupled with high morbidity
and mortality and global huge burden on the care givers plus
unsurmountable financial difficulties.
The two editorialists identified and highlighted certain pathways
underlying the physical activity and cardioprotection, which include
improvement in blood pressure, lipid profile, insulin sensitivity, body
weight, endothelial function, coronary blood flow and beneficial changes
in haemostatic and infammatory responses. There may exist other mechanisms
underlying this inverse relationship.
There is a converging evidence that multiple stressors arising from
numerous sources associated with revealed neuroimmunological and
endocrinological changes are one of the etiological denominators of
depression, which is reported to have high comorbidity with coronary
artery disease with poor outcome and enhanced mortality. Physical activity
is documented to have not only protective effect on depression but also on
the overall quality of life and general well being. Moreover, physical
activity also effects considerable improvement in the general mood of the
individual.
Unfortunately, a big chunk of world population is antagonistic to
regular physical exercises and hence with progressive age they tend to
develop aforesaid chronic but mostly fatal diseases. Sadly, many years of
relevant campaigns have not been very successful in changing such negative
attitudes of people against physical excercise. They have their choices-
good or bad-but in the shadow of solid findings of 50 years of research on
physical activity and its protective effect on cardiorespiratory fitness,
the two editorialists have brilliantly delivered this important message to
the audiences of the world.
Reference:
G David Batty and I-Min Lee. Physical activity and coronary heart
disease. BMJ 2004; 328: 1089-1090.
Competing interests:
Physical Exercise Supporter.
Competing interests:
No competing interests
10 May 2004
Dr. Naseem A. Qureshi, MD, IMAPA, LMIPS
Medical Director [A], Director, CME&R
Buraidah Mental Health Hospital, Postcode.2292, Saudi Arabia
Rapid Response:
Physical activity, coronary artery disease and depression: some connections!
Dear sir:
Notably, a large body of research data as also emphasized in this
impressive editorial by Batty and Lee (2004) suggests robustly the
protective effect of physical excercise in leisure time on the development
of coronary artery disease (CAD). Possibly, other diseases such as
diabetes mellitus, stroke, cancers, and osteoporosis are also positively
affected by physical exercise, which is reported to have an inverse
relationship with these diseases including CAD coupled with high morbidity
and mortality and global huge burden on the care givers plus
unsurmountable financial difficulties.
The two editorialists identified and highlighted certain pathways
underlying the physical activity and cardioprotection, which include
improvement in blood pressure, lipid profile, insulin sensitivity, body
weight, endothelial function, coronary blood flow and beneficial changes
in haemostatic and infammatory responses. There may exist other mechanisms
underlying this inverse relationship.
There is a converging evidence that multiple stressors arising from
numerous sources associated with revealed neuroimmunological and
endocrinological changes are one of the etiological denominators of
depression, which is reported to have high comorbidity with coronary
artery disease with poor outcome and enhanced mortality. Physical activity
is documented to have not only protective effect on depression but also on
the overall quality of life and general well being. Moreover, physical
activity also effects considerable improvement in the general mood of the
individual.
Unfortunately, a big chunk of world population is antagonistic to
regular physical exercises and hence with progressive age they tend to
develop aforesaid chronic but mostly fatal diseases. Sadly, many years of
relevant campaigns have not been very successful in changing such negative
attitudes of people against physical excercise. They have their choices-
good or bad-but in the shadow of solid findings of 50 years of research on
physical activity and its protective effect on cardiorespiratory fitness,
the two editorialists have brilliantly delivered this important message to
the audiences of the world.
Reference:
G David Batty and I-Min Lee. Physical activity and coronary heart
disease. BMJ 2004; 328: 1089-1090.
Competing interests:
Physical Exercise Supporter.
Competing interests: No competing interests