Intended for healthcare professionals

Rapid response to:

Papers

Parenteral metoclopramide for acute migraine: meta-analysis of randomised controlled trials

BMJ 2004; 329 doi: https://doi.org/10.1136/bmj.38281.595718.7C (Published 09 December 2004) Cite this as: BMJ 2004;329:1369

Rapid Response:

Number not to respond ?

This review leaves me a bitter taste. That metoclopramide can be statistically shown more effective than placebo is indeed good news.

But the number needed to treat is 4.

I understand 3 patients will not be relieved.I cannot be convinced that I should use this treatment alone in my emergency department.

We need randomised controlled trials of triptans vs cheap, widely used emergency department treatments: IV NSAIDs, neuroleptics, IV paracetamol, dihydroergotamin and their combinations.

Our ED migraineurs probably are not similar to most patients enrolled in RCTs led by neurologists. Neurologists treat migraine headaches that have not yet occurred and that they do not see, whereas emergency physicians actually see and treat ongoing migraines that probably are different since the patient goes to the ED.

Competing interests: None declared

Competing interests: No competing interests

11 December 2004
Axel Ellrodt
MD
American Hospital of Paris 92202 Neuilly France