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Withdrawal from paroxetine can be severe, warns FDA

BMJ 2002; 324 doi: https://doi.org/10.1136/bmj.324.7332.260 (Published 02 February 2002) Cite this as: BMJ 2002;324:260

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Symptoms on withdrawing from long term paroxetine

I'm a 31 year old woman from switzerland. 3 years ago, doctors in a
psychiatric clinic put me on paroxetine, 60 mg a day. Feelîng dizzy I
reduced it, after 2 weeks down to 40 mg/die. Now, after almost 3 years me
and my therapist decided that time has come to reduce it down to zero.
during 3 months we reduced it gradually in 10 mg steps until last
fridynight, when i took the last 10 mg. what then happened and what is
still happening seems like a nightmare to me. dizziness whenever I move my
eyes, "electronic shocks" going through my head, excessive sweating and
freazing at the same time. this is the fifth day and all I can do is lying
in my bed, hoping it will pass soon.
I've never experienced something like that and I withdrew also from other
antidepressants such a amitriptylin and mianserin.
Paroxetine definitely needs a re-evaluation, especially regarding
withdrawal in long time users.

Competing interests: No competing interests

05 May 2002
Elisabeth Kiss
Zurich, CH-8000