Group A Streptococci produce the serum opacity factor (SOF).
This factor cleaves the Apolipoprotein.
I think, this is one important pathogenetic factor.
It could induce upregulating Apolipoprotein A1!
Vascular complications would be the price.
Sincerily Yours
Friedrich Flachsbart
Kreikemeyer B, Martin DR, Chhatwal GS: SfbII protein, a fibronectin
binding surface protein of group A streptococci, is a serum opacity factor
with high serotype-specific apolipoproteinase activity.
FEMS Microbiol Lett 1999;178:305-311
Rapid Response:
Streptococci cleave Apolipoprotein A1
Dear Sir,
Group A Streptococci produce the serum opacity factor (SOF).
This factor cleaves the Apolipoprotein.
I think, this is one important pathogenetic factor.
It could induce upregulating Apolipoprotein A1!
Vascular complications would be the price.
Sincerily Yours
Friedrich Flachsbart
Kreikemeyer B, Martin DR, Chhatwal GS: SfbII protein, a fibronectin
binding surface protein of group A streptococci, is a serum opacity factor
with high serotype-specific apolipoproteinase activity.
FEMS Microbiol Lett 1999;178:305-311
Competing interests:
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Competing interests: No competing interests