Intended for healthcare professionals

Rapid response to:

Clinical Review

In search of “non-disease”

BMJ 2002; 324 doi: https://doi.org/10.1136/bmj.324.7342.883 (Published 13 April 2002) Cite this as: BMJ 2002;324:883

Rapid Response:

DISEASE DEFINITION

Dear Sirs
We have been taught and now teach that a disease should have four
components
A site of the lesion
A nature
A pathophysiology and
A dysfunction
and all together comprise of "a " disease for unless there is dysfunction
there can be no dis-ease or if there is dysfunction as in ageing but no
clear identifiable site or nature it cannot be disease. By default any
situation where these four components are not there, there is no disease.
This may be an attempt at oversimplification but conceptually sound,
however there are many diseases which have not been fully worked up and
all these four components
are not known.
Ashok Chandra

Competing interests: No competing interests

14 April 2002
ashok chandra
prof of medicine
K G MEDICAL COLLEGE, LUCKNOW ,INDIA