Experimental experience with a temporary intraluminal heparin-bonded polyurethane arterial shunt

Br J Surg. 1994 Feb;81(2):195-8. doi: 10.1002/bjs.1800810211.

Abstract

After vascular injury, intraluminal arterial shunting may be employed if definitive surgery must be delayed. This paper describes use of a heparin-bonded polyurethane shunt to restore distal circulation after ligation of the femoral artery in sheep. In studies to determine tissue viability for 12 h after insertion into the femoral artery, five of seven shunts remained patent. In another series of experiments to study tissue viability after limb ischaemia, the femoral artery was ligated and a tight Esmarch bandage applied to the limb for 6 h before shunt insertion. The shunt remained patent for 12 h in five of six cases. Nearly all shunt failures occurred shortly after placement and were attributable to intimal damage arising from difficulties during insertion.

MeSH terms

  • Anastomosis, Surgical
  • Animals
  • Blood Flow Velocity
  • Blood Vessel Prosthesis*
  • Body Temperature
  • Extremities / blood supply*
  • Extremities / physiopathology
  • Female
  • Femoral Artery / pathology
  • Femoral Artery / physiopathology
  • Femoral Artery / surgery*
  • Heparin / administration & dosage
  • Polyurethanes*
  • Sheep
  • Time Factors
  • Vascular Patency

Substances

  • Polyurethanes
  • Heparin