Higher frequency of neuroleptic-induced dystonia in mania than in schizophrenia

H A Nasrallah; C M Churchill; G A Hamdan-Allan

doi:10.1176/ajp.145.11.1455

Higher frequency of neuroleptic-induced dystonia in mania than in schizophrenia

Am J Psychiatry. 1988 Nov;145(11):1455-6. doi: 10.1176/ajp.145.11.1455.

Authors

H A Nasrallah¹, C M Churchill, G A Hamdan-Allan

Affiliation

¹ Department of Psychiatry, Ohio State University College of Medicine, Columbus 43210.

PMID: 2903686
DOI: 10.1176/ajp.145.11.1455

Abstract

In a study of 135 schizophrenic and 46 manic male patients treated with neuroleptics, a significantly higher proportion of the manic patients (26.1%) than of the schizophrenic patients (5.9%) developed acute dystonia. This suggests a higher vulnerability to acute extrapyramidal symptoms in mania.

Publication types

Comparative Study

MeSH terms

Acute Disease
Adult
Antipsychotic Agents / adverse effects*
Basal Ganglia Diseases / chemically induced
Bipolar Disorder / drug therapy*
Dyskinesia, Drug-Induced / etiology
Dystonia / chemically induced*
Humans
Male
Retrospective Studies
Schizophrenia / drug therapy*

Substances

Antipsychotic Agents