Randomized Questionnaire Based Case-Control Research Study on Evaluation of Sexual Function in Indian Patients Taking Oral Finasteride for Androgenetic Alopecia

Dermatol Ther (Heidelb). 2015 Dec;5(4):231-234. doi: 10.1007/s13555-015-0084-3. Epub 2015 Oct 5.

Abstract

Introduction: Finasteride is one of the most common drugs used in androgenetic alopecia. The literature discusses the sexual side effects of the drug; however, in practice there is little evidence to support this. The aim of the present study was to investigate the sexual dysfunction in patients taking finasteride 1 mg for androgenetic alopecia.

Methods: A questionnaire, based on the International Index of Erectile Function, was given to approximately 586 patients with androgenetic alopecia who were being treated with finasteride 1 mg for an average of 16 weeks. These patients were compared to an age-related control group who were attending the Dermatology Out Patients Department for various other skin ailments not related to hair disorders.

Results: Statistical analysis of the results showed no significant difference in the scores between patients taking finasteride and the control group.

Conclusion: Analysis showed no significant difference in sex-related problems with that of patients taking finasteride and age matched controls, suggesting that sex-related issues are not a side effect of finasteride.

Keywords: Androgenetic alopecia; Erectile dysfunction; Finasteride; Loss of libido; Male pattern baldness.