Associations of particulate matter with stroke mortality: a multicity study in Japan

J Occup Environ Med. 2013 Jul;55(7):768-71. doi: 10.1097/JOM.0b013e3182973092.

Abstract

Objective: Evidence linking short-term exposure to outdoor air pollution with hemorrhagic stroke is inconclusive.

Methods: We evaluated the effects of suspended particulate matter (SPM) on cardiovascular disease mortality, focusing on types of stroke, from March 2005 to December 2010, in five selected prefectures in western Japan. A multicity time-series analysis was used, and Asian dust was adjusted in the models.

Results: Even after adjusting for Asian dust, the same-day SPM was positively associated with several types of stroke mortality. Following a 10-μg/m increase in SPM, rate ratios were 1.014 (90% confidence interval [CI]: 1.002 to 1.026) for stroke, 1.030 (90% CI: 1.004 to 1.056) for intracerebral hemorrhage, and 1.016 (90% CI: 1.003 to 1.030) for ischemic stroke mortality.

Conclusions: Short-term exposure to outdoor air pollution may increase the risks of hemorrhagic stroke as well as ischemic stroke mortality.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Air Pollutants / adverse effects*
  • Air Pollutants / analysis
  • Air Pollution / adverse effects*
  • Air Pollution / analysis
  • Air Pollution / statistics & numerical data
  • Environmental Exposure / adverse effects*
  • Environmental Exposure / analysis
  • Environmental Exposure / statistics & numerical data
  • Humans
  • Japan / epidemiology
  • Models, Statistical
  • Particulate Matter / adverse effects*
  • Particulate Matter / analysis
  • Poisson Distribution
  • Regression Analysis
  • Stroke / etiology*
  • Stroke / mortality
  • Urban Health / statistics & numerical data*

Substances

  • Air Pollutants
  • Particulate Matter