Coronary artery diseaseComparison of Mortality Rates in Women Versus Men Presenting With ST-Segment Elevation Myocardial Infarction
Section snippets
Methods
The present retrospective study included all consecutive patients who had undergone percutaneous transluminal coronary angioplasty at our center from July 2002 to December 2004. These patients were divided into 2 cohorts according to their gender. All patients had provided written informed consent for the procedure, and ethical approval was waived, given the retrospective, observational design.
All patients had been pretreated with aspirin 100 mg/day and clopidogrel 75 mg/day or ticlopidine 250
Results
A total of 833 patients were selected, 210 women and 623 men. The clinical, angiographic, and procedural characteristics are summarized in Table 1, Table 2. Although the women were older and had greater rates of the most important cardiovascular risk factors, such as diabetes mellitus and hypertension, the men had more frequently reported a previous surgical or percutaneous revascularization. Also, the admission diagnosis showed significant differences, with greater rates of unstable coronary
Discussion
The most important findings of our long-term observational study were first that the men were more likely to report a previous cardiac event and women presented with greater rates of cardiovascular risk factors. Second, the long-term outcomes between the female and male patients were not statistically significant. Finally, great attention should be given to women presenting with a diagnosis of STEMI.
In our registry, the women had more risk factors than did the men. In contrast, the men had had
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Meta-Analysis of Gender Disparities in In-hospital Care and Outcomes in Patients with ST-Segment Elevation Myocardial Infarction
2021, American Journal of CardiologyCitation Excerpt :Although other factors including co-morbidities, primary PCI, antiplatelet usage, and delays to care had an impact to a lesser extent. This is consistent with other studies in which the gender gap in mortality was diminished after adjusting for covariates, particularly age.12,26-31 The gap in age at presentation might also explain the lack in changes in mortality rates by gender in the past 20 years, despite improvements in STEMI care (Supplemental Figure 2).
Analysis of reperfusion time trends in patients with ST-elevation myocardial infarction across New York State from 2004 to 2012
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2015, International Journal of CardiologyCitation Excerpt :The optimal management of these patients, apart from those with cardiogenic shock, remains to be determined. From a physiopathological point of view, plaques determining coronary stenosis not related to the culprit lesion may be evaluated either as a chronic condition [3], or as an expression of multiple unstable coronary lesions [4–8] with an unpredictable evolution. Clinically these different concepts have been translated into at least three strategies.
Individual trends in LDL-C control in patients with previous myocardial infarction
2020, REC: CardioClinicsCitation Excerpt :It is well known that male sex is a risk factor for developing coronary heart disease, but once it is established, no difference in risk for recurrent events should be made based on sex. This fact may wrongly influence the propensity of the treating physician when adjusting lipid-lowering drugs and based on patient sex,25 which may lead to different outcomes in the short26–28 and in the long term,29–32 although little is known about the correlation of proper LDL-C control, drug prescription and recurrent events in this population. We consider that the present data should warn us against instinctive, non-evidenced based risk perception and should prompt further research to clarify the reasons for a worse LDL-C control in women and non-diabetics.
Relation of Gender to the Occurrence of AKI in STEMI Patients
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Drs. D'Ascenzo and Gonella contributed equally to this report.