State of the art reportCerebral resuscitation after cardiac arrest: Research initiatives and future directions
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Cited by (141)
Clinical and microbiological features of drowning-associated pneumonia: a retrospective multicentre cohort study
2023, Clinical Microbiology and InfectionCitation Excerpt :Severity and organ dysfunctions were assessed using the Simplified Acute Physiology Score II (SAPS II) [12] and the Sequential Organ Failure Assessment (SOFA) score [13]. Neurological sequelae at the time of hospital discharge or on day 28, when the patients were still hospitalized, were evaluated using the Cerebral Performance Category score [14]. Continuous variables are reported as median (interquartile ranges [IQRs]) and categorical variables as proportions (%).
Intracranial pressure and autoregulation in trauma
2022, Cerebrospinal Fluid and Subarachnoid Space: Pathology and Disorders: Volume 2Predictors of survival and favorable neurological outcome in patients treated with targeted temperature management after cardiac arrest: A systematic review and meta-analysis
2018, Heart and LungCitation Excerpt :In our review, initial shockable rhythm was a predictor of outcome, which was in line with other studies.8,20 At the onset of cardiac arrest, initial non-shockable rhythm likely depletes oxygen earlier than shockable rhythm, which could lead to severe brain damage.35 For the above mentioned reasons, shockable rhythm may be a significant predictor of favorable outcome in patients treated with TTM.
Middle cerebral artery flow, the critical closing pressure, and the optimal mean arterial pressure in comatose cardiac arrest survivors—An observational study
2017, ResuscitationCitation Excerpt :Return of spontaneous circulation (ROSC) does not automatically restore cerebral perfusion. Cerebral perfusion failure after restoration of circulation is a well known phenomenon in animal models with no-reflow, cerebral hyperperfusion and hypoperfusion that ultimately restores toward normal cerebral blood flow (CBF).1 Humans have a similar flow pattern after cardiac arrest with low CBF in the initial phase after cardiac arrest that gradually restores toward normal values during the post-resuscitation syndrome.2–4
Research of the author's groups since the 1950s was supported by the US Army, the Pennsylvania Department of Health, the Asmund S Laerdal Foundation, and the National Institutes of Health.