Original ArticlesDuration of Pregnancy After Carbon Dioxide Laser Conization of the Cervix: Influence of Cone Height
Section snippets
Materials and Methods
This study was conducted at the Department of Obstetrics and Gynecology of Münsterlingen, Kantonsspital, Switzerland, from August 1, 1986, to December 31, 1994. Laser conization using the technique proposed by Dorsey and Diggs[9]was performed in 228 women younger than 35 years of age with cervical intraepithelial neoplasia (CIN). Patients were observed for reproductive events. Twenty-six patients were lost to follow-up. By December 31, 1996, 117 pregnancies occurred in 78 patients who had
Results
Sixty-four women who had singleton pregnancies after carbon dioxide laser conization of the cervix were included in the study. The indications for cervical conization were CIN grade 3 in 33 cases, grade 2 in 22 cases, and grade 1 in nine cases. The clinical characteristics of the study population are summarized in Table 1. There were no differences between cases and controls in the incidence of preterm delivery (six of 64 [9.4%] versus three of 64 [4.7%], respectively), preterm premature
Discussion
A MEDLINE search of the literature from January 1978 through January 1997 was performed to identify studies of pregnancy after carbon dioxide laser conization of the cervix. Search terms used, alone or in combination, were conization, cervix, pregnancy outcome, and preterm delivery. Our search indicates that this is the largest study of patients with singleton gestation after carbon dioxide laser conization of the uterine cervix, and it is the first report that demonstrates an association
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Margin status after loop electrosurgical excision procedure (LEEP) and laser excision in patients with high-grade cervical neoplasia
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Efficacy of laparoscopic and trans-abdominal cerclage (TAC) in patients with cervical insufficiency: A systematic review and meta-analysis
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2021, Clinical Microbiology and InfectionCitation Excerpt :The characteristics of the studies applying the Meijer protocol are summarized in Table S4, whereas the characteristics of the VALGENT studies are described in chapter 7 of the supporting information. For eight assays (Abbott RealTime [33–35], Anyplex HR [19,36,37], BD Onclarity [38–41], Cobas 4800 [20,42,43], Cobas 6800 [44,45], HPV-Risk [46–48], PapilloCheck [49,50] and Xpert HPV [51, 102]) non-inferior sensitivity and specificity for CIN2+ was demonstrated consistently in at least two studies, using the manufacturer defined test-cut-off and in addition sufficiently high intra- and inter reproducibility was documented. Alinity [52] and APTIMA [53] also fulfilled all criteria each in a single validation study, however the latter was evaluated also in multiple screening studies (see below).
Cervical Insufficiency
2016, Obstetrics: Normal and Problem PregnanciesLoop electrosurgical excision procedure and risk of miscarriage
2015, Fertility and SterilityCitation Excerpt :Women with a history of excisional cervical surgery are generally considered to be at increased risk of adverse pregnancy outcomes because of the potential loss of cervical integrity due to the procedure. The depth of tissue removed with the conization seems to be an important risk factor, and the majority of the studies indicate an increased risk of adverse pregnancy outcomes, such as preterm delivery, related to the length of tissue removed (1, 11, 16–19). Moreover, considering the physiologic process of healing and remodelling of the cervix after a surgical procedure, it seems to be biologically plausible that the time elapsed from LEEP to pregnancy is another important risk factor for obstetric complications.