Original researchContinuous glucose monitoring for the evaluation of gravid women with type 1 diabetes mellitus
Section snippets
Materials and methods
The initial study sample consisted of 41 consecutive gravid women with type 1 diabetes who were recruited for this prospective study during a routine clinical visit to the Diabetes in Pregnancy Center of the Perinatal Division Unit, Rabin Medical Center between November 2001 and March 2002. Of these, 34 women (82.9%) gave consent to participate after receiving a comprehensive explanation of the study. The local ethics committee approved the study protocol.
In all cases, type 1 diabetes mellitus
Results
Mean patient age was 26 ± 4.7 years (range 21–36 years), and mean gestational age was 25 ± 6.2 weeks (range 16–32 weeks). Mean gravidity and parity were 2.4 ± 1.1 and 1.2 ± 0.9, respectively. Mean BMI was 26.2 ± 4.7 kg/m2, mean HbA1c level 6.1 ± 1.2% (normal range 4.5–5.7%), and mean fructosamine level 276 ± 29 mg/dL (normal range 205–285 mg/dL).
All patients completed the 3-day study. There were no adverse events associated with the use of continuous glucose monitoring. None of the patients
Discussion
Despite years of meticulous study, there is still a paucity of information regarding the optimal level of glycemia in diabetic pregnancy that clinicians should target to safely reduce maternal and perinatal morbidity. Strict metabolic control in patients with type 1 diabetes has been associated with an increased risk of maternal hypoglycemia. In our study, continuous monitoring of blood glucose in women with diabetic pregnancies confirmed the high occurrence rate of nocturnal hypoglycemia
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Cited by (70)
Consensus guidelines for glycemic monitoring in type 1/type 2 & GDM
2014, Diabetes and Metabolic Syndrome: Clinical Research and ReviewsReal-time continuous glucose monitoring (CGM) integrated into the treatment of type 1 diabetes: Consensus of experts from SFD, EVADIAC and SFE
2012, Diabetes and MetabolismCitation Excerpt :On the other hand, data from the literature on the use of professional CGM show the following results: professional CGM makes it possible to diagnose missed peaks of hyperglycaemia in postprandial periods during pregnancy, both in gestational and pre-existing type 1 diabetes [44,45]; the repeated use (5 to 7 days every 4 to 6 weeks) of CGM in the course of pregnancy improves HbA1c and reduces the risk of macrosomia in both type 1 and type 2 diabetes [46].
Continuous Glucose Monitoring in Pregnancy
2024, Obstetrics and GynecologyContinuous Glucose Monitoring Feedback in the Subsequent Development of Gestational Diabetes: A Pilot, Randomized, Controlled Trial in Pregnant Women
2023, American Journal of Perinatology