Risk factors for rapid-onset cervical cancer☆,☆☆
Section snippets
Methods
The current study is part of a population-based investigation undertaken in Connecticut to examine patterns of cervical cancer screening and ways in which screening could be improved to further reduce cervical cancer incidence.10, 14 After institutional review board approval, all histologically confirmed incident cervical cancer cases were sought by a rapid ascertainment system set up through the Connecticut tumor registry. During the period from March 1, 1985, through February 23, 1990, 664
Results
Analysis was performed on the 329 women classified as having normal-onset cervical cancer, 111 women classified as having possible rapid-onset cancer, and 43 women with rapid-onset disease. Women diagnosed with rapid-onset tumors were found to differ significantly from those diagnosed with normal-onset disease with respect to all demographic and clinicohistologic factors examined (Table I).Factor Empty Cell
Comment
Consistent with previous reports, we observed that women classified as having rapid-onset cervical cancer were more likely than normal-onset cases to be diagnosed with glandular tumors (adenocarcinomas and adenosquamous carcinomas).9 Although glandular tumors have been reported to account for 10% to 20% of cervical cancer cases, among our group of rapid-onset cases nearly 42% of cases were diagnosed with a carcinoma containing a glandular component.19 The suggestion that glandular tumors of the
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Cited by (110)
Cervical Cancer in Women Aged 35 Years and Younger
2016, Clinical TherapeuticsCitation Excerpt :It seems improbable for young women to develop advanced disease, given the classic teaching that the risk of progression from mild dysplastic changes of the cervix to severe dysplasia, let alone cancer, is only 1% per year.3 Therefore, the development of cancer in young women, especially the very young, has led to the theory that cervical cancer in the very young must be more aggressive.4 Others blame changes in sexual behavior with an earlier age of first intercourse, greater frequency of multiple partners and HPV infection, and tobacco use for the observations.5–8
Younger age distribution of cervical cancer incidence among survivors of pediatric and young adult cancers
2014, Gynecologic OncologyCitation Excerpt :The effect of being a survivor on age at cervical cancer diagnosis could thus be attributable to potential differences in screening between the populations. Furthermore, cervical adenocarcinomas have been reported to progress more rapidly than the more common squamous cell carcinomas [11]. The effect of being a survivor on age at cervical cancer diagnosis could also thus be attributable to potential differences in the distribution of adenocarcinoma diagnoses between survivors and the general US population.
HPV genotyping in adenocarcinoma of the uterine cervix in Thailand
2013, International Journal of Gynecology and ObstetricsScreening Adolescents and Young Women
2013, Obstetrics and Gynecology Clinics of North AmericaDeterminants of an integrated cervical cancer screening services in primary healthcare: sharing lessons from Kisumu, Kenya
2023, Journal of Public Health in Africa
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Reprint requests: Allan Hildesheim, PhD, Interdisciplinary Studies Section, Environmental Epidemiology Branch, DCEG, National Cancer Institute, 6130 Executive Blvd, Room 443, Rockville, MD 20852.
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