Clinical studyFrequency of diabetic ketoacidosis and hypoglycemic coma during treatment with continuous subcutaneous insulin infusion. Audit of medical care
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Cited by (69)
Novel function of transthyretin in pancreatic alpha cells
2012, FEBS LettersCitation Excerpt :Thus, the primary role of glucagon is correcting hypoglycemia caused by malnutrition, fasting, and treatment of diabetes to achieve normoglycemia [6–9]. Insulin treatment in diabetes, especially type 1 diabetes, greatly increases the risk of hypoglycemia, with effects on a number of organs including brain, and causes critical systemic symptoms such as hypoglycemic coma [10–12]. In addition, an absent glucagon response plays a prominent role in a failure to correct hypoglycemia induced by insulin and may exacerbate critical systemic symptoms [8].
Therapy in APS: Criteria and fundamentals for the utilization of insulin pump
2009, FMC Formacion Medica Continuada en Atencion PrimariaTreatment of diabetes mellitus using an external insulin pump: the state of the art
2008, Diabetes and MetabolismUse of New Technologies for Monitoring and Treating Diabetes in Pregnancy
2007, Obstetrics and Gynecology Clinics of North AmericaCitation Excerpt :A few early studies indicated a high rate of ketoacidosis with CSII [39,40]. But as patients and caregivers became more experienced with the technique, the frequency of ketoacidosis decreased [41]. Several remediable factors increased the likelihood of ketoacidosis during the first experiences with CSII, including physician inexperience (poor choice of infusion rates, poor instructions to patients, and so forth), the use of unbuffered insulin (which can cause cannula blockage), cannula dislodgment or leakage, and unsuitable patients (poorly compliant).
Endocrine emergencies: Hypoglycemic and hyperglycemic crises
2005, Textbook of Endocrine SurgeryImplantable closed-loop glucose-sensing and insulin delivery: The future for insulin pump therapy
2002, Current Opinion in Pharmacology
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Dr. Bending was supported by Nordisk Gentofte.