Letters
Drug prevention of hypertension
Assumptions and extrapolation
BMJ 2009; 338 doi: https://doi.org/10.1136/bmj.b2600 (Published 29 June 2009) Cite this as: BMJ 2009;338:b2600- Sripal Bangalore1,
- Franz H Messerli2
- 1Division of Cardiology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02445, USA
- 2St Luke’s Roosevelt Hospital and Columbia University College of Physicians and Surgeons, New York, NY, USA
- sbangalore{at}partners.org
Law and colleagues’ conclusion, that blood pressure should be lowered in everyone over a certain age, rather than measured in everyone and treated in some, is derived from 147 disparate trials.1 The trials have varying inclusion/exclusion criteria, and were conducted in patients aged 34-84, with follow-up of 0.5-8.4 years, and in those with hypertension, after myocardial infarction, with coronary artery disease without myocardial infarction, and with heart failure. …
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