Table 6

 Risk of cardiovascular death according to longitudinal changes in dietary PUFA, stratified by sources of oxidative stress

SubgroupRisk of cardiovascular death
nHazard ratio (95% CI)P
LA intervention group only (n=207; per 5 en% increase in n-6 LA†)
Alcohol use* (kcal/day; 1 kcal=4.18 kJ)
 Moderate/heavy (>200 kcal/day)791.70 (1.18 to 2.46)<0.01
 Light (<200 kcal/day )711.09 (0.69 to 1.72)0.71
 None 571.40 (0.79 to 2.50)0.25
Smoking status*
 Yes1471.55 (1.12 to 2.12)0.01
 No601.08 (0.67 to 1.68)0.75
Whole sample (n=429; per 5 en% increase in unspecified PUFA)
Alcohol use* (kcal/day)
 Moderate/heavy (>200 kcal/day)1621.66 (1.23 to 2.25)<0.01
 Light (<200 kcal/day)1501.43 (1.00 to 2.04)0.05
 None 1170.91 (0.65 to 1.28)0.60
Smoking status*
 Yes3011.46 (1.15 to 1.86)<0.01
 No1281.08 (0.79 to 1.49)0.62

En%=percentage of food energy.

*Assessed at acute hospital admission.

†From safflower oil.