Table 1

Total number of cases of cancer in offspring (including familial cases) by age of offspring at diagnosis and number of familial cancer cases in which parents were affected with concordant cancer

Cancer and age (years) at diagnosis in offspring	No of cases in offspring	No of familial cases by parental age (years) at diagnosis*
Cancer and age (years) at diagnosis in offspring	No of cases in offspring	<40	40-49	50-59	60-69	70-79	80-89	≥90
Colorectal
0-76	24 121	28	94	292	654	890	572	66
<60	12 972	28	87	212	387	523	310	26
60-76	11 149	0	7	80	267	367	262	40
Lung
0-76	16 545	2	10	138	342	456	157	8
<60	8198	1	6	99	204	252	76	4
60-76	8347	1	4	39	138	204	81	4
Breast
0-76	58 505	120	575	1084	1472	1384	787	104
<60	43 655	119	522	926	1212	1064	547	72
60-76	14 850	1	53	158	260	320	240	32
Prostate
0-76	36 878	0	7	168	1234	2580	1465	101
<60	9837	0	5	94	626	1121	516	27
60-76	27 041	0	2	74	608	1459	949	74
Urinary bladder
0-76	9662	1	10	42	114	158	101	11
<60	5156	1	8	25	62	81	55	6
60-76	4506	0	2	17	52	77	46	5
Melanoma
0-76	20 804	45	90	140	171	148	88	5
<60	16 844	45	87	128	156	118	68	3
60-76	3960	0	3	12	15	30	20	2
Skin squamous cell carcinoma
0-76	6998	0	2	8	52	107	125	36
<60	3633	0	2	6	31	61	50	14
60-76	3365	0	0	2	21	46	75	22
Non-Hodgkin’s lymphoma
0-76	9687	2	3	26	63	59	49	3
<60	6736	2	2	22	48	37	32	1
60-76	2951	0	1	4	15	22	17	2

*If both parents were affected with concordant cancer, minimum age at onset in either parent was used.