Table 1

 Long term mortality from cardiovascular* and other causes in women with pre-eclampsia during first singleton pregnancy

Outcome of first pregnancyNo of womenAll deathsCardiovascular deathsNon-cardiovascular deaths†
No of deaths (per 1000)Adjusted hazard ratio (95% CI)‡No of deaths (per 1000)Adjusted hazard ratio (95% CI)‡No of deaths (per 1000)Adjusted hazard ratio (95% CI)‡
All women
No pre-eclampsia 801 32322 107 (27.6)1.0 (reference)2380 (3.0)1.0 (reference)18 456 (23.0)1.0 (reference)
All pre-eclampsia34 824902 (25.9)1.1 (1.0 to 1.1)176 (5.1)1.9 (1.6 to 2.2)660 (19.0)0.93 (0.86 to 1.00)
No pre-eclampsia, term birth712 18119 214 (27.0)1.0 (reference)2011 (2.8)1.0 (reference)16 129 (22.6)1.0 (reference)
Term pre-eclampsia26 708674 (25.2)1.0 (0.94 to 1.1)115 (4.3)1.6 (1.4 to 2.0)512 (19.2)0.92 (0.85 to 1.01)
Preterm pre-eclampsia5886169 (28.7)1.4 (1.2 to 1.6)45 (7.6)3.7 (2.7 to 4.8)111 (18.9)1.08 (0.89 to 1.31)
Women with one lifetime pregnancy
No pre-eclampsia, term birth112 2085311 (47.3)1.9 (1.8 to 1.9)596 (5.3)2.0 (1.8 to 2.2)4382 (39.1)1.8 (1.8 to 1.9)
Term pre-eclampsia4758227(47.7)1.8 (1.6 to 2.1)47 (9.9)3.4 (2.6 to 4.6)163 (34.3)1.6 (1.4 to 1.9)
Preterm pre-eclampsia142692 (64.5)3.1 (2.5 to 3.9)29 (20.3)9.4 (6.5 to 13.7)57 (40.0)2.3 (1.7 to 3.0)
Women with two or more lifetime pregnancies
No pre-eclampsia, term birth599 97313 903 (23.2)1.0 (reference)1415 (2.4)1.0 (reference)11 746 (19.6)1.0 (reference)
Term pre-eclampsia21 950447 (20.4)1.0 (0.90 to 1.1)68 (3.1)1.5 (1.2 to 2.0)349 (15.9)0.93 (0.84 to 1.04)
Preterm pre-eclampsia446077 (17.3)1.1 (0.87 to 1.4)16 (3.6)2.4 (1.5 to 3.9)54 (12.1)0.89 (0.68 to 1.2)

*Ischaemic heart disease and stroke combined, excluding other circulatory conditions (see table 2).

†Excluding all circulatory conditions.

‡Adjusted for maternal education (three categories), maternal age at first birth, and year of first birth.