Table 2

 Effect of tranexamic acid on fatal and non-fatal thrombotic events in patients with traumatic bleeding. Figures are numbers (percentages) of patients experiencing each event

Tranexamic acid (n=6684)Placebo (n=6589)Odds ratio (95% CI)P value
Any event98 (1.5)140 (2.1)0.69 (0.53 to 0.89)0.005
Any arterial event47 (0.7)80 (1.2)0.58 (0.40 to 0.83)0.003
Myocardial infarction23 (0.3)46 (0.7)0.49 (0.30 to 0.81)0.005
Stroke28 (0.4)40 (0.6)0.69 (0.43 to 1.11)0.128
Any venous event60 (0.9)71 (1.1)0.83 (0.59 to 1.17)0.295
Pulmonary embolism42 (0.6)47 (0.7)0.88 (0.58 to 1.33)0.548
Deep vein thrombosis25 (0.4)28 (0.4)0.88 (0.52 to 1.50)0.641